He is made by Plankton as a way to detect Krabby Patties to the "smallest molecule of a Krabby Patty." This, however, backfires when Plankton accidentally pushes the switch to start it, accidentally sucking him in. He then goes through the many equipments. The Analyzer outputs that Plankton is made of "30% mean guy," "20% spiteful monster," and "50% evil butt-head," which from here he concludes that the sample is "100% big jerk."
The Analyzer then praises Karen's new screensaver. Plankton, being fed up with him, destroys him with a wrench.
Plankton was previously analyzed as 1% evil 99% hot gas in the episode "Plankton!"