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SpongeBob's Great Grandmother (possibly Great Great Grandma SquarePants or Great Grandma BubbleBottom) is one of eight possible great grandmothers of SpongeBob SquarePants. She is mentioned by SpongeBob when he accidentally calls Plankton, who he thinks is his great grandma, "great great grammy-maw."
She and her husband may have had SpongeBob's Great Grandmother.