An extremely rich man named Howard Blandy comes into the Krusty Krab and asks Mr. Krabs to retire from his business for a large sum of money. Mr. Krabs happily accepts, leaving SpongeBob and Squidward with a simple "See you around," causing SpongeBob to cry hysterically. Afterwards, a new manager called Carl the Fish comes to them, renaming The Krusty Krab "Krabby O'Monday's." Mr. Krabs drives by, but ignores it, instead going to the newly opened Bikini Bottom Hook Museum, then when he is trying to paint a bowl of fruit, he actually paints a bowl of Krabby Patties, followed by a round of golf; however, he then realizes that he hates golf. Mr. Krabs has done everything he wanted to do and decides to go home, where he realizes he has nothing to do. He tries to talk to his daughter Pearl, but Pearl kicks Mr. Krabs out of the house and tells him to get a job. Downtrodden, Mr. Krabs goes to the beach to look for a job, but hits a glass door, with a sign saying "Help Wanted." It is one of the glass doors of the Krabby O' Monday's, so he goes inside to take a look at what job is vacated.
Meanwhile, Carl wants Squidward to have more spirit, so he threatens Squidward with a muscular Human Resources guy if he does not continuously smile. Fearful, Squidward continues his work with a forced smile. Mr. Krabs gets a job at the Krabby O'Monday's working as a busboy, listening to SpongeBob complain about the problems. The problems are that the patties are processed and there is an automated cash register, with no one watching it. Angered, Mr. Krabs complains, only to be ignored by Carl. He also finds out how the new patties are synthetically engineered, fake and disgusting. Now furious, Mr. Krabs shows the customers what the food is actually made of and the customers find out that the patties are made out of gray material. So they run away, making the restaurant unpopular. Carl calls Howard to tell him what Mr. Krabs is doing. Mr. Krabs plugs the fake patty maker up, but escaping, processing slush and the pressurized air inside cause the whole restaurant to explode. Mr. Krabs retakes ownership of the destroyed restaurant by giving all his money back to Howard and changes the restaurant's name back to "The Krusty Krab," saying that he got back the love of his "two best friends," that is, until the episode ends with a demand for Squidward and SpongeBob to clean up the mess. Then Mr. Krabs presses the cash register, causing dollar bills to appear in the screen, making it black and the episode ends.
The synthetic patties may be clam or jellyfish manure as the substance closely relates to the manure seen in "Sleepy Time" and "Pest of the West."
The Krabby O'Monday's patties being made with grey glop may be a reference to McDonald's using "pink slime" in their burgers. However, McDonald's discontinued the use of pink slime, and other fast-food chains followed suit.
This is the first time Mr. Krabs works at the Krusty Krab (though it was called the Krabby O'Monday's) as an employee. The second will be in "Gullible Pants."
The customers did not seem to notice that the patties were synthesized until Mr. Krabs revealed it.
Krabby O'Monday's is possibly a cross between the fictional Krusty Krab and real-life casual dining restaurants like O'Charley's, Beef O'Brady's, and especially TGI Friday's. The employees all wear colorful lapel buttons on their vests. The restaurant also has red-and-white pinstripe tables, which used to be a trademark of TGI Friday's.
The trailer that has the suitcases full of money says "U Pull" on the side. This is a parody to U Haul.
The gray gunk in the Synthetic Krabby Patties could be a possible reference to McDonald's using "pink slime" in their burgers.
Cha-Ching is a variation on the song "Rinkle rinkle" from the Mr. Magoo Christmas Carol TV movie from 1962. Originally sung by the character Scrooge, who Mr. Krabs was quite heavily based on.
When Mr. Krabs sings about sounds and sights, he slams a bird in his book. However, this does not make sense because birds don't live underwater.
All the customers flee after they see the garbage they were eating. When Krabby O'Monday's gets flooded with the garbage, all the customers are back in the restaurant.
Mr. Krabs asked Blandy "Do I still get the money?," Blandy said "Of course," but the closed-captions say "Yes."
After Pearl kicks Mr. Krabs out of the house, he searches for metal on the beach with his metal detector. However, he walks into the Krabby O'Monday's in the middle of the beach. When he looks up at it, he is not at the beach anymore, he's standing on the Krabby O' Mondays parking lot.
Frank has a female voice when he says "What did he say? Garbage?".
All the customers scream when they run out of the Krabby O'Mondays, but their mouths are closed.