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This article contains speculative information. Please keep this in mind as you read it.
Although Plankton and Karen are married they fight a lot for an example in "Single Cell Anniversary" they fought when Plankton never gave Karen a present for there anniversary but Plankton soon learns from SpongeBob that he has to show his love and plays a romantic song for Karen. Karen also comes up with Plankton's plans a lot but he always says he comes up with the plan. Although the two fight a lot Karen still likes Plankton like in "Enemy In-Law" where Karen was jealous of Mama Krabs. Plankton also doesn't let Karen help him that much like in "Salsa Imbecilicus" where he muted her and didn't let her even help make the Salsa.