This weapon has a built-in switch which, if flipped, would make anyone in a certain radius very confused, hence its title. The confusion is also accompanied with "duhhh" noises and salivation from the mouth and tongue.
Its only appearance was in "Mermaid Man and Barnacle Boy III." At the beginning of the episode, SpongeBob accidentally gets confused from touching the switch, but he is stopped. Later, SpongeBob and Patrick attempt to use the orb of confusion to stop Man Ray from wreaking havoc, only to use it on themselves when SpongeBob flips the switch.
The Orb of Confusion was briefily shown in the Truth or Square Video Game at level "Meeting MMM and BB!!!".