This motel was used by the B.G.A.T.F.B.C. (Bad Guys All Together For Book Club). The villains only entered their room to find two anonymous men in their room that claimed they were the I.J.L.S.A (International Justice Lodge of Super Aquantices). These men then took off their trench coats to show they were Mermaid Man and Barnacle Boy.
A battle unleashed in the room until when the villains were tied up in the Hairnet of Knowledge, they revealed what the acronym was for.
This motel was shown in the lost episode of Mermaid Man and Barnacle Boy, meaning this motel is either shut down, destroyed, or turned into another line of business.
It would be impossible for Mermaid Man, Barnacle Boy, and the other superheroes to enter the motel since only villians or the evil can enter the motel, hence the name. They may have snuck in or enter in another sleuthing manner.