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Mayo, short for Mayonnaise, is a sauce made of olive oil and eggs. It's sometimes used on a Krabby Patty. It first appears in the episode " Nature Pants."
Mayo as a weapon.
In " Nature Pants," SpongeBob gives Patrick a Mayo pot.
In " Hooky," according to Mr. Krabs, the only perspective of being in a Tuna can is the smell of mayo.
In " Mermaid Man and Barnacle Boy II," SpongeBob has trouble opening a jar of mayo. He uses the Conch Signal to call Mermaid Man and Barnacle Boy to help him.
In " Band Geeks," Squidward reveals that mayonnaise is not an instrument, after Patrick asks if it is. This has become a popular meme on the Internet.
In " Just One Bite," Harold has a lot of mayo on his patty and Squidward thinks it is disgusting.
In " Hocus Pocus," SpongeBob turned Patrick into mayo, after Patrick asked him to.
In " Planet of the Jellyfish," the Jellions' weakness is mayo. As a result, the replicas are not fond of it. SpongeBob and Sandy made use of mayo to defeat the Jellions and the Evil Alien Jellyfish Overlord.
In , mayo is used as a weapon against The SpongeBob Movie: Sponge Out of Water Plankton's Tank Robot and for a strange reason all the customers want to hold the Mayo from the Krabby Patty.
At the end of the movie, it's also revealed that SpongeBob's pet snail, Gary, hates mayonnaise--SpongeBob used it as a way to trick Plankton, who was disguised as Gary at the time to steal the formula, by giving him a Krabby Patty with extra mayo.