Jerktonium is contained in the jar hanging from the ceiling
Jerktonium is a fictional element seen in "It's a SpongeBob Christmas! "The antidote for it is the song Don't Be a Jerk (It's Christmas).
Appearance and Effects
Jerktonium is a green-colored material that is known to change the Bikini Bottomites into jerks when ingested. Infected victims develop big black eyebrows, black bags around their eyes, and a mass of black stubble around their mouths.
The only two known to be immune to Jerktonium is SpongeBob, due to his pure heart, small brain, and innocent love of Christmas, and Squidward, humerously due to his complete lack of compation and non-socialness.
History
Plankton discovered the material and planned to use it on people in Bikini Bottom to make himself look good compared to them. His first victim to use it against was SpongeBob. He made SpongeBob try the Jerktonium-laced fruitcake but it didn't work on him making Plankton angrily gift the Jerkmaker-9000 to SpongeBob. Shortly after that, SpongeBob (unknowingly) gives fruitcakes contaminated with Jerktonium to everybody in Bikini Bottom after obtaining the Jerkmaker-9000 from Plankton.
Seeing that the Jerktonium worked on other people in Bikini Bottom except SpongeBob, Plankton constructed a robot known as "ToyBob" to wreak havoc in Bikini Bottom which ruined SpongeBob's reputation.
Later SpongeBob realizes that people in Bikini Bottom were acting like jerks so he decided to ask Sandy for help. After getting help, SpongeBob sings the song "Don't be a Jerk (It's Christmas)" to cure everyone; they join in. When Santa arrived around at the Krusty Krab, he prepares to give everyone (except Plankton) coal and gives Plankton the Secret Formula from Mr. Krabs. Shortly after, ToyBob, arrives to wreak havoc, but SpongeBob defeats him with the Jerkmaker-9000 in time to save Bikini Bottom. This caused Plankton's plan to get the Secret Formula to fail due to Santa identifying, from ToyBob's remains, that the robot actually belonged to Plankton himself. After that, Plankton is put back in the Naughty list, and everyone gets a present while Plankton surrenders the formula and gets a bag of coal tipped over his head.