Plankton is sick of his computer "wife" Karen, Plankton spots Mama Krabs and falls in love with her. Plus, he turns off Karen. Convinced that this just another trick aimed at getting the family formula for Krabby Patties (which was not), Krabs tries to reveal Plankton's schemes and break up the ill-favored fling. Krabs decides to break up that fishy relationship before he winds up with the world's tiniest stepfather and before Plankton finally gets the secret formula for Krabby Patties. While accusing Plankton for the "scheme" he reveals to Plankton that his mother knows the secret recipe giving Plankton an opportunity. However, the robot (Plankton had created) causes the downfall of their relationship and finds out about Plankton's scheme after he tells her. Then, he gets flung out of the Krusty Krab by her and Karen gets turned back on as he bounces off the "on" button. Plankton insulted her and she threatens him with a lazer, Plankton quickly corrects himself but Karen (who is still mad for turning her off) zaps him anyway.
I can turn into a skyscraper!
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Betsy Krabs has a Scottish accent, where Mr. Krabs has an entirely different accent altogether.
It is unknown what happened to Plankton's robot after this episode, or how its relationship with Mama Krabs worked out.
Ironically, Besty Krabs prefers a relationship with a machine, just as Plankton went for Karen, a computer.
Karen zaps Plankton when she's angry with him. She would do this to him again when he sends her to the frozen tundra in "Frozen Face-Off."
When Plankton calls Betsy, Plankton shows Betsy Krabs's number (Betsy Krabs's number is 791347).
This episode takes place after "The Abrasive Side" because in that episode, he did not know what the word, "Overtime" means. In this episode, he uses it.
In Greek, this episode is called Όλα για τη συνταγή του καβουροπάτι which means All for the Krabby Patty recipe.
MY LEG: Mr. Krabs saying "SpongeBob!"
The Nickelodeon schedule calls this episode "My Worst Friend's Wedding." It was also the original title for this episode.
In Indonesia, Plankton didn't kidnapped the people to eat, but to become the ingredients, so that it could be cannibalism.
During the scene that Plankton is kicked out of the Krusty Krab by Mama Krabs, he quotes the poem "In Memoriam" by Alfred, Lord Tennyson.
When Mr. Krabs jumps at Plankton, he bellows like Tarzan.
When Plankton, Mr. Krabs, Betsy and SpongeBob say each other names at the Krusty Krab, it is a reference to the dinner scene in Shrek 2.
Betsy Krabs showing her muscle and in it being a battleship is a reference to the Popeye cartoons.
When Mr. Krabs barges into the Chum Bucket in anger, some scenes show red pipes on the wall, but some don't.
Plankton's phone is missing the number zero in this episode.
Plankton asked SpongeBob if his tie was on straight, yet he is not wearing a tie, he is wearing a bow-tie.
When Plankton walks into the Krusty Krab with the rose, there is a burger sticker on the window. However, once he's inside, it's no longer there. This happens a few seconds later when Mrs. Krabs walks in. This also happens in "The Krabby Kronicle."