|First appearance:||"Evil Spatula"|
|Latest appearance:||"Evil Spatula"|
Disulfide is mainly a pink liquid in a small bottle. It also has a yellow label with the words "DANGER! EXPLOSIVE" written in red on it.
Disfulfide is a compound that causes other items to explode when mixed together. This was first shown when SpongeBob only put two drops into a mixture and the explosion blows up him and Mr. Krabs. Plankton poured an entire bottle of it after being tricked into doing so by Mr. Krabs. The explosion completely destroys the Chum Bucket and injures Plankton and even nearly destroys Karen.